| Date | Location | Result | |
| May 23, 2021 | Stillwater, OK | Oklahoma State 10, Mississippi State 2 | Box score |
| May 22, 2021 | Stillwater, OK | Mississippi State 12, Campbell 0 | Box score |
| May 22, 2021 | Stillwater, Okla. | Oklahoma State 9, Mississippi State 3 | Box score |
| May 21, 2021 | Stillwater, OK | Mississippi State 3, Boston University 1 | Box score |
| May 13, 2021 | Tuscaloosa, AL | Florida 6, Mississippi State 2 | Box score |
| May 12, 2021 | Tuscaloosa, AL | Mississippi State 3, Ole Miss 1 | Box score |
| May 09, 2021 | Starkville, MS | Mississippi State 4, Georgia 3 | Box score |
| May 08, 2021 | Starkville, MS | Mississippi State 4, Georgia 2 | Box score |
| May 07, 2021 | Starkville, MS | Mississippi State 4, Georgia 2 | Box score |
| May 05, 2021 | Starkville, MS | Mississippi State 6, Tennessee 2 | Box score |
| May 05, 2021 | Starkville, MS | Mississippi State 2, Tennessee 1 | Box score |
| May 02, 2021 | Columbia, S.C. | Mississippi State 7, South Carolina 1 | Box score |
| May 01, 2021 | Columbia, S.C. | Mississippi State 6, South Carolina 2 | Box score |
| Apr 30, 2021 | Columbia, S.C. | South Carolina 8, Mississippi State 7 | Box score |
| Apr 25, 2021 | Starkville, MS | Texas A&M 8, Mississippi State 1 | Box score |
| Apr 24, 2021 | Starkville, MS | Mississippi State 8, Texas A&M 1 | Box score |
| Apr 23, 2021 | Starkville, MS | Texas A&M 7, Mississippi State 5 | Box score |
| Apr 20, 2021 | Starkville, MS | Mississippi State 10, Jackson State 3 | Box score |
| Apr 20, 2021 | Starkville, MS | Mississippi State 8, Jackson State 0 | Box score |
| Apr 18, 2021 | Columbia, Mo. | Missouri 6, Mississippi State 5 | Box score |
| Apr 17, 2021 | Columbia, Mo. | Missouri 4, Mississippi State 3 | Box score |
| Apr 17, 2021 | Columbia, Mo. | Missouri 5, Mississippi State 2 | Box score |
| Apr 14, 2021 | Starkville, MS | Mississippi State 3, Southern Miss 2 | Box score |
| Apr 13, 2021 | Birmingham, AL | Mississippi State 8, Samford 5 | Box score |
| Apr 10, 2021 | Ruston, La | Oklahoma 9, Mississippi State 0 | Box score |
| Apr 10, 2021 | Ruston, LA | Mississippi State 2, Louisiana Tech 0 | Box score |
| Apr 07, 2021 | Starkville, MS | Mississippi State 4, Central Arkansas 3 | Box score |
| Apr 05, 2021 | Hammond, La. | Southeastern La. 6, Mississippi State 4 | Box score |
| Apr 03, 2021 | Florence, Ala. | Mississippi State 9, North Alabama 1 | Box score |
| Apr 03, 2021 | Florence, Ala. | Mississippi State 9, North Alabama 7 | Box score |
| Mar 31, 2021 | Hattiesburg, MS | Mississippi State 2, Southern Miss 1 | Box score |
| Mar 28, 2021 | Fayetteville, Ark. | Arkansas 4, Mississippi State 3 | Box score |
| Mar 27, 2021 | Fayetteville, Ark. | Arkansas 8, Mississippi State 7 | Box score |
| Mar 26, 2021 | Fayetteville, Ark. | Arkansas 2, Mississippi State 0 | Box score |
| Mar 21, 2021 | Starkville, MS | Florida 8, Mississippi State 0 | Box score |
| Mar 20, 2021 | Starkville, MS | Florida 10, Mississippi State 0 | Box score |
| Mar 19, 2021 | Starkville, MS | Florida 1, Mississippi State 0 | Box score |
| Mar 15, 2021 | Oxford, Miss. | Ole Miss 8, Mississippi State 0 | Box score |
| Mar 14, 2021 | Oxford, Miss. | Ole Miss 4, Mississippi State 1 | Box score |
| Mar 13, 2021 | Oxford, Miss. | Ole Miss 6, Mississippi State 0 | Box score |
| Mar 10, 2021 | Starkville, MS | Mississippi State 5, Memphis 0 | Box score |
| Mar 09, 2021 | Montgomery, Ala. | Mississippi State 10, Alabama State 4 | Box score |
| Mar 07, 2021 | Starkville, MS | Mississippi State 5, Western Kentucky 4 | Box score |
| Mar 06, 2021 | Starkville, MS | Mississippi State 6, Alcorn State 5 | Box score |
| Mar 06, 2021 | Starkville, MS | Mississippi State 10, Western Kentucky 0 | Box score |
| Mar 05, 2021 | Starkville, MS | Mississippi State 16, Alcorn State 0 | Box score |
| Mar 05, 2021 | Starkville, MS | Mississippi State 8, Ball State 3 | Box score |
| Mar 03, 2021 | Tuscaloosa, AL | Alabama 4, Mississippi State 0 | Box score |
| Feb 28, 2021 | Waco, Texas | Baylor 10, Mississippi State 6 | Box score |
| Feb 27, 2021 | Austin, TX | Mississippi State 3, Houston 0 | Box score |
| Feb 27, 2021 | Austin, TX | Texas 8, Mississippi State 7 | Box score |
| Feb 26, 2021 | San Marcos, TX | Mississippi State 6, Texas State 2 | Box score |
| Feb 26, 2021 | San Marcos, TX | Texas State 4, Mississippi State 3 | Box score |
| Feb 24, 2021 | Starkville, MS | Mississippi State 10, Miss. Valley St. 2 | Box score |
| Feb 22, 2021 | Starkville, MS | Mississippi State 10, Miss. Valley St. 1 | Box score |
| Feb 22, 2021 | Starkville, MS | Mississippi State 5, Missouri State 0 | Box score |
| Feb 21, 2021 | Starkville, MS | Southern Illinois 6, Mississippi State 5 | Box score |
| Feb 21, 2021 | Starkville, MS | Mississippi State 4, Stephen F. Austin 2 | Box score |
| Feb 13, 2021 | Starkville, MS | Mississippi State 10, Miami (Ohio) 3 | Box score |
| Feb 13, 2021 | Starkville, MS | Mississippi State 10, Miami (Ohio) 9 | Box score |